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How Much Tylenol for a 21 Lb Baby

Consumer drug brand owned past Johnson & Johnson

Tylenol
Extra Strength Tylenol and Tylenol PM.jpg

Tylenol PM (left) and Tylenol

Production type Analgesic
Possessor McNeil Consumer Healthcare
Country Usa
Introduced 1955 (1955)
Markets Worldwide
Tagline For What Matters Most
Website www.tylenol.com Edit this at Wikidata

Tylenol () is a brand of drugs advertised for reducing pain, reducing fever, and relieving the symptoms of allergies, common cold, cough, headache, and influenza. The agile ingredient of its original flagship product is paracetamol (known in the U.s., Canada, and diverse other countries as acetaminophen), an analgesic and antipyretic. Similar the words paracetamol and acetaminophen, the brand name Tylenol is derived from a chemical name for the compound, Northward-acetyl-para-aminophenol (APAP).[1] The brand proper name is owned past McNeil Consumer Healthcare, a subsidiary of Johnson & Johnson.[2]

As of 2020[update], the "Tylenol" brand was used in Brazil, Canada, China, Egypt, Kuwait, Lebanon, Lithuania, Mexico, Myanmar, the Netherlands, Oman, Paraguay, the Philippines, South Africa, Republic of korea, Switzerland, Taiwan, Thailand, the U.s., Uruguay, Venezuela, and Vietnam.[iii]

Medical uses [edit]

The active ingredient in Tylenol is paracetamol, a widely used over-the-counter analgesic (pain reliever) and antipyretic (fever reducer).[iv] [5] Formulations with additional active ingredients intended to target specific applications are sold under the Tylenol brand. These can include codeine every bit co-codamol, dextromethorphan, methocarbamol, guaifenesin, pseudoephedrine, caffeine, diphenhydramine, chlorpheniramine and phenylephrine.[half-dozen]

History [edit]

The brand was introduced in 1955 by McNeil Laboratories, a family-owned pharmaceutical manufacturer. Two brothers took over the visitor from their male parent that year, and one of them after learned well-nigh paracetamol, which was non on the U.S. market place at that fourth dimension. To avert competing with aspirin, they marketed it as a product to reduce fever in children, packaging information technology similar a red burn truck with the slogan, "for little hotheads". The brand proper noun Tylenol and the United States Adopted Proper noun acetaminophen were generated by McNeil from the chemic proper name of the drug, Northward-acetyl-para-aminophenol (APAP).[vii]

In 1955, McNeil introduced Tylenol Elixer for children, the first aspirin-free pain reliever.[8]

Johnson & Johnson bought McNeil in 1959, and one year later the drug was made bachelor over the counter.[7] [viii]

Recalls [edit]

1982 Chicago Tylenol murders [edit]

On September 29, 1982, a "Tylenol scare" began when the first of seven individuals died in the Chicago metropolitan area afterward ingesting Extra Forcefulness Tylenol that had been deliberately contaminated with cyanide. Inside a week, the company pulled 31 million bottles of tablets back from retailers, making it one of the first major production recalls in American history.[ix]

Equally a event of the crisis, all Tylenol capsules were discontinued, as were capsules of other brand names. Retained by McNeil's president, new product consultant Martin Calle of management strategist Calle & Company conceived the globe's first tamper-resistant gelatin-enrobed capsule called "Tylenol Gelcaps",[8] which proved to resuscitate the 92% of sheathing-segment sales lost to the recall.[ citation needed ] The tamper-resistant, triple-sealed safety containers were placed on the shelves of retailers ten weeks later the withdrawal, and other manufacturers followed suit. The crisis toll the company more than US$100 million, only Tylenol regained 100% of the market share it had before the crisis. The Tylenol murderer was never institute, and a US$100,000 reward offered past Johnson & Johnson remained unclaimed equally of 2013.[10]

Before the poisonings, Tylenol brands held effectually 35% of the Usa market for acetaminophen and in the immediate backwash, brutal to viii%. Within a year sales had rebounded to the prior levels.[xi] J&J'south handling of the crisis has been widely cited as an example of optimal crisis management.[12]

These events led to the widespread utilise of tamper resistance packaging of drugs by drug companies, to the 1982 passage of a US federal law making tampering a offense, and to legislation in 1989 requiring tamper-proof packaging.[11]

2010 Tylenol recalls [edit]

On January xv, 2010, a voluntary recall of several hundred batches of popular medicines was announced, including Benadryl, Motrin, Rolaids, Simply Sleep, St. Joseph Aspirin, and Tylenol.[13] The recall was due to complaints of a musty smell suspected to be due to contamination of the packaging with the chemic 2,iv,6-tribromoanisole.[14] The total health effects of two,iv,half-dozen-tribromoanisole are non known but no serious events have been documented in medical literature.[15] The call back came 20 months later on McNeil first began receiving and investigating consumer complaints almost moldy-smelling bottles of Tylenol Arthritis Relief caplets, co-ordinate to the U.S. Nutrient and Drug Administration (FDA). The recall included 53 million bottles of over-the-counter products, involving lots in the Americas, the United Arab Emirates, and Fiji.[16]

Children's Tylenol [edit]

On Apr xxx, 2010, another recall was issued for twoscore products including liquid infant and children'south pain relievers Tylenol and Motrin, and allergy medications Zyrtec and Benadryl.[16] An FDA report said its inspectors found thick grit and grime roofing certain equipment, a hole in the ceiling, and duct record-covered pipes at the Fort Washington, Pennsylvania, facility that fabricated 40 products recalled. New testing regulations were enacted later on the recall to ensure product quality and safety.[17]

On May 5, 2010, the FDA confirmed[xviii] that the bacterium found at the Johnson & Johnson establish that made the recalled Children's Tylenol was Burkholderia cepacia, a bacterium often resistant to common antibiotics.[19] The bacteria were plant on the exterior of sure product-containing drums, but not in the finished product. The CDC has stated that Burkholderia cepacia is not likely to crusade health issues for those with healthy allowed systems, but those with weaker ones and those with chronic lung diseases, such every bit cystic fibrosis, could be more than susceptible to infection.[ citation needed ]

Advertizing [edit]

Tylenol has many different advertizement approaches. One of these advertising campaigns focuses on "getting you back to normal", whereas the other commercials focus on Tylenol's current slogan, "Feel better, Tylenol". In the "Feel meliorate, Tylenol" commercials, Tylenol places emphasis on the importance of sleep; diverse people are seen sleeping in this commercial while a voiceover describes how sleep can assist repair and heal the human body during times of aches and pains.[xx] In the "getting yous back to normal" commercial, Tylenol places more emphasis on helping its consumers go back to their daily routines; many dissimilar people are shown first experiencing headaches and other sorts of body pain, where a voiceover then states that Tylenol Rapid Release can assistance rid aches and pains; the diverse people are then shown enjoying their everyday lives, and are seen as "back to normal".[21]

In an older commercial from 1986, Tylenol emphasized that it is the drug that American hospitals trust the most. In this advertisement, Susan Sullivan told the consumer that Tylenol was a drug that could be trusted by Americans since many doctors also trusted it; she went on to state that doctors prescribed Tylenol iv times more often than other leading hurting relieving drugs combined.[22]

A form that contains dextromethorphan, pseudoephedrine, acetaminophen, and chlorpheniramine, is sold as Cotylenol.[23] [24]

Countries [edit]

Every bit of 2021[update], the "Tylenol" brand was used in Australia [25] Brazil, Canada, Cathay, Egypt, Kuwait, Lebanon, Mexico, Myanmar, Netherlands, Oman, Paraguay, the Philippines, S Africa, South korea, Switzerland, Taiwan, Thailand, the Us, Uruguay, Venezuela, and Vietnam.[iii]

See also [edit]

  • Listing of paracetamol make names

References [edit]

  1. ^ West, Nancy. "History of Tylenol" (PDF). Nancy West Communications. Retrieved July 26, 2014.
  2. ^ Euromonitor International. "Acetaminophen benefits from concerns surrounding safety of analgesics". Market Inquiry World. Retrieved July 26, 2014.
  3. ^ a b "Paracetamol international brands". Drugs.com. Retrieved January 24, 2020.
  4. ^ Aghababian, Richard Five. (October 22, 2010). Essentials of Emergency Medicine. Jones & Bartlett Publishers. p. 814. ISBN978-i-4496-1846-nine.
  5. ^ Ahmad, Jawad (October 17, 2010). Hepatology and Transplant Hepatology: A Case Based Approach. Springer. p. 194. ISBN978-ane-4419-7085-five.
  6. ^ "Pain Relief Products for Adults & Children". Tylenol . Retrieved August 11, 2017.
  7. ^ a b Miller, Stephen (May 26, 2010). "Creator of Tylenol 'For Fiddling Hotheads'". The Wall Street Journal.
  8. ^ a b c "TYLENOL® History". TYLENOL® . Retrieved February 13, 2022.
  9. ^ Rehak, Judith (March 23, 2002). "Tylenol made a hero of Johnson & Johnson : The retrieve that started them all". The New York Times . Retrieved July 3, 2019.
  10. ^ "FBI drops 1982 Tylenol murders chore force, local constabulary to pb probe". ABC. September 27, 2013. Retrieved June 9, 2021.
  11. ^ a b Markel, Howard (September 29, 2014). "How the Tylenol murders of 1982 changed the way we swallow medication". PBS NewsHour.
  12. ^ Dezenhall, Due east. (March 17, 2004). "Tylenol Tin't Cure All Crisis". USA Today . Retrieved October 8, 2007.
  13. ^ Singer, Natasha (January 15, 2010). "In Call up, a Office Model Stumbles". The New York Times . Retrieved July 3, 2019.
  14. ^ Tylenol recall expands, WebMD, accessed ane-17-2010.
  15. ^ "McNeil Consumer Healthcare Announces Voluntary Call up of Certain Over-The-Counter (OTC) Products in the Americas, UAE, and Republic of the fiji islands" (Press release). McNeil Consumer Healthcare. Jan 15, 2010. Retrieved July 3, 2019.
  16. ^ a b Wahba, Phil; Gevirtz, Leslie (May four, 2010). "FACTBOX-Johnson & Johnson's contempo product recalls". Reuters.
  17. ^ Heavey, Susan (May four, 2010). "FDA finds crud at J&J found, urges use of generics". Reuters.
  18. ^ Kavilanz, Parija (May 5, 2010). "Bacteria identified in Tylenol recall". CNN. Retrieved July 3, 2019.
  19. ^ Kavilanz, Parija (May 6, 2010). "Bacteria identified in Tylenol recollect". CNN. Retrieved July 21, 2010.
  20. ^ Archived at Ghostarchive and the Wayback Machine: Midori's Tylenol Commercial. Baronial 23, 2009 – via YouTube.
  21. ^ Archived at Ghostarchive and the Wayback Auto: Tylenol Rapid Release - Suzumiya Haruhi. September 12, 2008 – via YouTube.
  22. ^ Archived at Ghostarchive and the Wayback Machine: Tylenol Commercial (1986). Baronial xix, 2007 – via YouTube.
  23. ^ "Co-Tylenol Drug Information, Indications & Other Medicaments on Catalog.md". Retrieved December x, 2016.
  24. ^ "CoTylenol oral : Uses, Side Effects, Interactions, Pictures, Warnings & Dosing - WebMD". Retrieved December 10, 2016.
  25. ^ "Most Us". Retrieved September 17, 2021.

External links [edit]

  • Official website Edit this at Wikidata
  • Gerth, Jeff; Miller, T. Christian (September 21, 2015). "New Court Docs: Maker of Tylenol Had a Plan to Block Tougher Regulation". ProPublica.
  • Gerth, Jeff; Miller, T. Christian (October 14, 2015). "New Trial Records: Doctors Recommended Tylenol - But Only at Lower Doses". ProPublica.

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Source: https://en.wikipedia.org/wiki/Tylenol_(brand)

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